Directions

DRIVING

From San Francisco or points on the west side of San Francisco Bay:

Take I-80 East to the Bay Bridge.  Treasure Island is a left exit at the end of the San Fracnisco side span.  The exit road will merge onto the road that runs down the west side of Yerba Buena Island (overlooking San Francisco to the west and Clipper Cove to the east). Continue down the hill until you reach the gate that guards the entrance to Treasure Island.  Continue through the gate and take your first right onto California Ave. 
As you proceed down California, you will see several large buildings on your right. After the last building, turn right on Avenue "I". Drive straight (south) along the building to the facility.

From Oakland or points on the east side of San Francisco Bay:
Take I-80 west to the Bay Bridge.  After the toll booths, merge into the far left lane.  The exit for Yerba Buena/Treasure Island is a left exit at the end of the Oakland side span.  Follow the exit road around to the west side of Yerba Buena Island. At the stop sign, merge onto the road that takes you down to the gates of Treasure Island.  Continue through the gate and take your first right onto California Ave. 
As you proceed down California, you will see several large buildings on your right. After the last building, turn right on Avenue "I". Drive straight (south) along the building to the facility. 

PUBLIC TRANSPORTATION
From San Francisco, take the MUNI 108 from the Transbay Terminal on Mission St.  Get off at the California Ave/Avenue I stop on Treasure Island. Turn left when you get off the bus and make a right on Avenue "I", just past the big building. Walk south along the building and you will see the TISC facility straight ahead.

More direction links:
Google Maps
Yahoo Maps
Mapquest